HPC Cloud Updates WE 21 Dec 2025

Updates to AWS, Azure & GCP in the last week relevant for HPC practitioners. It might be the week before Christmas but it doesn’t look like anyone is slowing down! Google gives us an alternative to PCS, we have some new VMs from AWS and Azure NetApp gets some upgrades.

HPC Cloud Updates WE 21 Dec 2025

AWS

Dropping costs and getting a speedup is always nice!

How AstraZeneca improved their genomics processing to be 60% faster, 70% more cost-effective | Amazon Web Services
AstraZeneca’s genomic research requires extensive computational resources to analyze DNA sequences for developing life-saving therapies. As cloud infrastructure evolves with more powerful capabilities, customers can adopt them to see performance and efficiency gains. AstraZeneca successfully migrated to Amazon EC2 F2 instances for genomics, boosting performance by 60% and slashing costs by 70%.

M8gn and M8gb (network and EBS optimised variants) are now generally available, In N. Virginia and Oregon for now.

Now generally available: Amazon EC2 M8gn and M8gb instances - AWS
Discover more about what’s new at AWS with Now generally available: Amazon EC2 M8gn and M8gb instances

You can now use Zone IDs when creating VMs rather than just names

Amazon EC2 now supports Availability Zone ID across its APIs - AWS
Discover more about what’s new at AWS with Amazon EC2 now supports Availability Zone ID across its APIs

New regional instances: C8a in Spain, R8i and the the flex version now in Seoul, Sao Paulo and Tokyo, C8g in Zurich, M8g in Thailand, Jakarta, Melbourne and the UAE, R8g in Paris and Hyderabad, C8i and the flex version in Singapore, M8i in Seoul, Tokyo, Sydney, Singapore and Canada, M8i-flex in Sydney AND London finally gets some M7a


Azure

Azure NetApp gets cross region replication and ransomware protection

Azure updates | Microsoft Azure
Subscribe to Microsoft Azure today for service updates, all in one place. Check out the new Cloud Platform roadmap to see our latest product plans.
Azure updates | Microsoft Azure
Subscribe to Microsoft Azure today for service updates, all in one place. Check out the new Cloud Platform roadmap to see our latest product plans.

Google Cloud

Have Google brought the fight to AWS PCS? Cluster Director looks like a fully managed way to run Slurm for HPC on Google Cloud including planning your deployment. All just after Nvidia announced its acquisition of Slurm.

Cluster Director is now generally available | Google Cloud Blog
For AI and HPC workloads, Cluster Director is now GA, and Cluster Director support for Slurm on Google Kubernetes Engine (GKE) is now in preview.